Dr. Peter Martin On Future Treatment Options for Mantle Cell Lymphoma

In this video from OncLive, Dr. Peter Martin discusses potential changes in the future treatment of younger patients with mantle cell lymphoma (MCL), as well as new lines of therapy currently being developed for all patients with MCL. These new therapies include Bruton’s tyrosine kinase inhibitors, PI3 kinase inhibitors, Bcl-2 inhibitors, immunomodulatory drugs, and immunotherapy agents.

In the Lymphoma Program our patient care is informed by our clinical research. A full listing of available trials for MCL can be found on our clinical trials website.

REDLAMP 15: Outcomes for Patients with Mantle Cell Lymphoma after Ibrutinib

While ibrutinib represents undeniable progress in the treatment of mantle cell lymphoma, the outcomes and ideal management of patients that experience ibrutinib failure are unclear. In a study recently published in Blood, Dr. Peter Martin discusses findings from a recent observational study from 15 sites on patients who experienced lymphoma progression while receiving ibrutinib.

Previous #REDLAMP entries can be viewed on our Youtube channel.

We encourage you to follow the Lymphoma Program on Twitter, Youtube, and Facebook where we will highlight new videos are about research publications as they are released. We also welcome your feedback, suggestions and questions about this project. If you have other questions about our lymphoma program or clinical trials or would like to see one of our lymphoma specialists, please contact us at 212-746-2919.

Dr. Peter Martin Discusses Transplantation as a Treatment Option for Patients with Mantle Cell Lymphoma

In an interview with the Lymphoma Research Foundation (LRF), Dr. Peter Martin discusses mantle cell lymphoma (MCL), treatment options including transplantation, and what advice he would give to people who are newly diagnosed with MCL.

Debate exists among researchers on whether or when stem cell transplantation should be used in the treatment of MCL. Why do you think this is so?

“Some people feel that stem cell transplantation is likely to make a patient live longer and others feel that a long remission duration following a stem cell transplant means there are fewer lymphoma-related side effects, and everybody likes that idea.

On the other hand, autologous stem cell transplantation doesn’t cure MCL. There are limited data that suggest that it may allow people to live longer, and many patients may experience significant side effects but not have a very durable remission and a longer life. So that’s a very subjective sort of decision based on less than perfect evidence.

It’s our job as lymphoma doctors to help patients understand the potential benefits and the potential negative side effects to all treatment options so they can select a treatment that is best for them. There’s no right or wrong treatment option in many cases and it’s a matter of choosing the option that makes the most sense for that person at that point in time.”

The full interview can be read on the LRF’s website.